Platelet Count

Platelets, also called thrombocytes, are tiny fragments of cells that are essential for normal blood clotting. Platelets are formed from very large cells called megakaryocytes. So it is in the bone marrow and are released into the blood to circulate. The platelet count is a test that determines the number of platelets in a person’s sample of blood.

These steps result in the formation of a loose platelet plug at the site of the injury in a process called primary hemostasis. Activated platelets support the coagulation cascade, a series of steps that involves the sequential activation of proteins called clotting factors. This secondary hemostasis process results in the formation of strands of fibrin that weave through the loose platelet plug, form a fibrin net, and compress to form a stable clot that remains in place until the injury has healed.

Each component of primary and secondary hemostasis must be present. Activated at the right time, and functioning properly for adequate clotting. But if there are insufficient platelets, or if platelets are not functioning normally, a stable clot may not form and a person may be at an increased risk of excessive bleeding.

Platelets survive in the circulation of about 8 to 10 days. The bone marrow must continually produce new platelets. It is to replace those that degrade, are used up, and/or are lost through bleeding. Determining the number of platelets in blood with a platelet count can help diagnose a range of disorders. So it having to do with too few or too many platelets. (https://labtestsonline.org)

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